Jessica’s Stage 4 BRAF Mutation Colon Cancer Story
Interviewed by: Taylor Scheib
Edited by: Katrina Villareal
Jessica was diagnosed with stage 4 colon cancer at 26. Four months before her diagnosis, she began experiencing intense episodes of stomach cramps, diarrhea, and vomiting, which would last for 48 hours. She initially thought she had a gluten intolerance and visited emergency doctors several times. They misdiagnosed her with gastroenteritis and prescribed ineffective medication
Frustrated by the recurring symptoms, Jessica pushed for blood tests, suspecting something more serious. During a particularly severe episode of stomach cramps, she called an ambulance and was taken to the hospital. Blood tests revealed that she was severely anemic, requiring multiple blood transfusions. A subsequent CT scan suggested the presence of a tumor in her colon. Despite some reluctance from doctors to comment on the findings, a colonoscopy confirmed the diagnosis.
Jessica described the colonoscopy as a traumatic experience since she was awake during the procedure and could sense something was wrong. Afterward, she was told she had a tumor blocking part of her colon, causing her digestive issues. Although it wasn’t immediately confirmed as cancerous, Jessica underwent surgery to remove half of her colon (a hemicolectomy), during which 36 lymph nodes were tested. The results showed that the cancer had spread, confirming stage 4 colon cancer.
Jessica faced a roller coaster of emotions when told she had the BRAF genetic mutation, which is resistant to chemotherapy. However, a post-surgical PET scan revealed no remaining cancer in her body, which was a miracle. Despite the initial bleak prognosis, she completed six months of chemotherapy and has been in remission since November 2022.
Throughout chemotherapy, Jessica experienced manageable side effects, including fatigue and neuropathy. Mentally, she remained optimistic, having come to terms with living a fulfilling life regardless of her prognosis. Her treatment gave her a new perspective on life, changing her outlook on relationships and personal boundaries. She acknowledged grieving her old self but ultimately embraced her transformed identity.
Jessica’s message to others is that they are stronger than they realize. She encourages people to see difficult experiences as temporary and reminds them that life can look vastly different in a year, offering opportunities for growth and new perspectives.
- Name: Jessica T.
- Diagnosis:
- Colon Cancer
- Staging:
- Stage 4
- Mutation:
- BRAF
- Symptoms:
- Severe stomach cramps
- Diarrhea
- Vomiting
- Anemia (discovered later)
- Treatments:
- Surgery: hemicolectomy (removal of half the colon)
- Chemotherapy
This interview has been edited for clarity. This is not medical advice. Please consult with your healthcare provider for treatment decisions.
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Raquel A., Colorectal Cancer, Stage 4
Symptoms: Frequent bowel movements, pin-thin stools, mild red blood in stool
Treatments: Chemotherapy (oxaliplatin, 5-fluorouracil, and irinotecan)
Symptoms: Blood in stool, changes in bowel habits, feeling gassy/bloated
Treatments: Surgery to remove tumor, chemotherapy (FOLFIRI), monoclonal antibody (panitumumab), liver transplant
Jessica T., Colon Cancer, Stage 4, BRAF Mutation
Symptoms: Severe stomach cramps, diarrhea, vomiting, anemia (discovered later)
Treatments: Surgery (hemicolectomy), chemotherapy