Bleomycin Side Effects & Stories
Read patient experiences with the antibiotic drug, bleomycin, used in chemotherapy. For medical information on bleomycin, check with your doctor.
Background: Bleomycin is usually given by injection to treat several cancers, including (but not limited to): cervical, Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and testicular cancers1.
Bleomycin Side Effects
Some of the most common reported side effects from Bleomycin include, but are not limited to2:
- Itching
- Rash
- Nausea
- Vomiting
- Weight loss
- Changes to skin color
Patient Stories by Side Effect
Hodgkin’s Lymphoma Stories
“I got ABVD chemo for the first two cycles, which was four rounds. For the rest of the eight treatments, it was just the AVD.
They took out the B drug (bleomycin) because my PET scan after the first four treatments showed that I had no evidence of disease. They were able to take out the bleomycin since it can be hard on your lungs.”
“I think the nausea got a little better without the bleomycin, but it was still pretty killer. One less medicine is always a relief.”
“My doctor is very much into clinical trials and research at a global scale. When I was going through treatment, he had just learned of a study that realized that if you pull bleomycin, the B in “ABVD,” halfway through your infusion schedule, it really has no effect on the remission rate.”
“What impressed me about my new oncologist’s unique approach to this standard treatment was its dynamicity. It involved a mid-treatment PET/CT scan to determine if it was possible to downgrade the chemo regimen from the classic ABVD to a less intense AVD, thereby dropping the “B” (bleomycin) after just one of the six cycles.
Bleomycin is one of those nasty chemo drugs that can have detrimental long-term effects on your lungs. The less of it your body has to endure, the better, and his treatment approach was very mindful of that.”
Testicular Cancer Stories
“Typically, anyone who is diagnosed with testicular cancer and needs chemo goes on the BEP regimen. Each cycle takes three weeks, and it’s three cycles, so it’s nine weeks.
However, after the first cycle, I had complications with the Bleomycin in my lungs. That’s not uncommon. Since I had those complications, they had to stop that particular chemo drug and continue with an extra two rounds of the EP.”
All Patient Stories with Bleomycin
Nicole M., Hodgkin's, Stage 4
Cancer details: Staged 2 then 4 after second opinion
1st Symptoms: Extreme fatigue, persistent itching on lower half of legs
Treatment: 6 cycles (12 infusions) chemo, ABVD then AVD (dropped bleomycin)
...
Mara T., Stage 2BX (Bulky)
1st Symptoms: Shortness of breath, back pains, daily migraines
Treatment: 3 rounds of ABVD, 3 rounds AVD, Radiation
Topics: Self-advocacy, mental health
...
Erica H., Hodgkin's, Stage 3B
Cancer details: Staged at 3B
1st Symptoms: Intense itchiness, fatigue, night sweats, weight loss
Treatment:ABVD chemotherapy, 6 cycles (12 infusions)
...
Hugo T., Non-Seminoma, Stage 2B
Age at Diagnosis: 21
1st Symptoms: Pea-sized lump on right testicle
Treatment: Surgical removal of right testicle, lymph node resection, chemotherapy
...
Steve L., Non-Seminoma, Stage 4
Age at Diagnosis: 25
1st Symptoms: Grape-sized tumor on neck; hip and pelvis pain; ultrasound revealed tumor on right testicle
Treatment: Chemotherapy (BEP), removal of right testicle, lymph node resection (RPLND), and tumor dissection in the neck
...
References
1. Bleomycin. Medline Plus, U.S. National Library of Medicine, 15 Aug 2011, https://medlineplus.gov/druginfo/meds/a682125.html.
2. Brandt, Josiah P.; Gerriets,Valerie. “Bleomycin.”Bookshelf, U.S. National Library of Medicine, 18 Sept 2020, https://www.ncbi.nlm.nih.gov/books/NBK555895/.