Diffuse Large B-Cell Lymphoma (DLBCL) Patient Stories
Diffuse large b-cell lymphoma (DLBCL) is a common subtype of b-cell non-Hodgkin’s lymphoma, and is usually an aggressive cancer, one that progresses quickly.
Explore below to hear DLBCL patient stories and experiences. Our community members share their first symptoms of non-Hodgkin’s lymphoma, how they made treatment decisions, their entire treatment experience, recovery, and navigating quality of life issues.
DLBCL General Information
First Symptoms
Commonly reported first symptoms of non-Hodgkin’s lymphoma in general include, but are not limited to:
- Swollen or enlarged lymph nodes
- Sudden and/or acute weight loss
- Appetite loss
- Night sweats
- Extreme fatigue
- Fever
- Unexplained itchiness
Patient Stories on Symptoms
How I Knew I Had Non-Hodgkin’s Lymphoma
Explore patient stories on the first signs they knew something was wrong.
Treatment
The most common treatment for DLBCL is a four-drug chemotherapy regimen, known as CHOP:
- C – Cyclophosphamide
- H – Doxorubicin Hydroxydaunomycin
- O – Vincristine Sulfate (Onvocin)
- P – Prednisone
Oftentimes, it’s combined with a monoclonal antibody known as rituximab or Ritxuan, known altogether as R-CHOP.
One alternative chemo regimen is dose-adjusted or DA-R-EPOCH:
- R – Rituximab
- E – Etoposide Phosphate
- P – Prednisone
- O – Vincristine Sulfate (Oncovin)
- C – Cyclophosphamide
- H – Doxorubicin Hydrochloride (Hydroxydaunorubicin)
Patient Stories on Treatments
Hear from patients on their R-EPOCH chemotherapy regimen experiences.
DLBCL Patient Stories
Hear From DLBCL Patients
Tony W., Relapsed T-Cell/Histiocyte-Rich Large B-Cell Lymphoma (T/HRBCL)
Symptoms: A lot of effort needed cycling, body wasn’t responding the same; leg swelling
Treatments: R-CHOP chemotherapy, CAR T-cell therapy
Stephanie Chuang
Stephanie Chuang, founder of The Patient Story, celebrates five years of being cancer-free. She shares a very personal video diary with the top lessons she learned since the Non-Hodgkin lymphoma diagnosis.
Shahzad B., Refractory Diffuse Large B-Cell Lymphoma (DLBCL), Stage 4
Symptoms: Extreme fatigue
Treatment: R&B, R-ICE, R-EPOCH, CAR T-cell therapy (cell-based gene therapy)
Symptoms: Chest pain, back pain, bump on neck, night sweats Treatment: Chemotherapy, CAR T-Cell therapy
Robyn S., Relapsed Diffuse Large B-Cell Lymphoma (DLBCL), Stage 2E
Symptoms: Enlarged lymph nodes
Treatments: Chemotherapy: R-CHOP, R-ICE, intrathecal, BEAM; autologous stem cell transplant, head and neck radiation, CAR T-cell therapy
Richard P., Relapsed/Refractory Follicular Lymphoma & DLBCL
Relapse Symptoms Swelling in leg, leg edema Treatment: R-CHOP chemotherapy, clinical trial (venetoclax-selinexor)
Quality of Life Topics
Fertility Preservation
Fertility preservation is not always an option for cancer patients, but when treatments like chemotherapies are involved, our community members recommend that you ask about it. This includes procedures like egg retrieval and freezing, as well as sperm banking.
Exercise for DLBCL Management: Expert Insights from Dr. Joshua Brody
Dive into the valuable benefits of exercise for DLBCL patients and provide practical tips to help integrate physical activity into your daily life.
Fertility Preservation & Cancer Treatments
Read patient stories on how they approached fertility preservation after a cancer diagnosis.
Patient Details Egg Retrieval Before Cancer Treatment
A detailed look at the egg harvesting and retrieval from a cancer patient who went through the process before starting chemotherapy.
Hair loss
Hair loss, often experienced after chemotherapy, is one of the first things that comes to mind for many patients when they first hear a cancer diagnosis.
Patients describe on how they managed through losing their hair after cancer treatments.
Financial toxicity
Trying to deal with a cancer diagnosis is overwhelming enough, but for many patients and their families, there’s the added stress of trying to figure out how to pay for cancer treatment.
Details on how Medicare can help cover (some) cancer-related costs.
Guidance From Experienced Hospital Social Worker
Hear more from an expert on how patients and caregivers can approach issues like insurance and paying for treatment.
Dealing with emotional and mental stress
Scanxiety: Waiting For Test Results
Read how patients worked through the anxiety of waiting for results from tests and scans, known as “scanxiety.”
Leaving the Hospital: Emotions & Support
Read on for answers from real cancer patients about how can you navigate the feelings that come along with hospital stays.